This resource provides information on familial motor neuron disease and some of the challenges that may arise with genetic testing for the condition.

What you should know

• About 10% of MND is ‘familial’, which means there is or has been more than one MND affected person in a family.
• Learning about the genetics of MND, genetic testing, gene mutations, clinical trials and other MND research can help to better inform people affected by familial MND.
• Understanding of the genetic mutations related to MND has increased over time, and is accelerating due to advances in technology and collaboration between researchers.
• In Australia, recent research has found that the C9orf72, SOD1 and other MND-related gene mutations are present in 60.8% of all people with familial MND.